What is CBD oil? How can it help you with your health problems?
Cannabis plants have soared in popularity over the past few years. CBD oil is among the top products that consumers are seeking nowadays. But what could be the reason behind the success of CBD in the market?
Recently in the month of June 2018, the Food and Drug Administration approved the medical use a certain drug called Epidiolex for the management of epilepsy. This medication is essentially the purified form of CBD oil.
Perhaps this approval by the FDA could be one of the reasons why consumers are gaining confidence in the health benefits of CBD oil. Although it was previously viewed as a treatment option for people who are seriously ill, nowadays it is actually used to manage any form of pain.
What Is CBD Oil
Cannabidiol oil is derived from Cannabidiol – one of the 104+ chemical compounds known commonly as cannabinoids. Cannabinoids are compounds found in the cannabis plant.
What is it made from?
Cannabidiol CBD oil is essentially a liquid concentrate prepared from Cannabidiol. Its production from a product similar to tetrahydrocannabinol has raised controversies whether CBD and tetrahydrocannabinol THC are actually the same things with similar effects.
CBD manufactures start by selecting hemp plants that are highly rich in CBD to increase the overall yield. Although THC is the major compound of cannabis plants, CBD comes in as the second most abundant substance.
Due to the ever-increasing demand for CBD products, proprietary strains of cannabis with a high yield of CBD have been developed. These plants provide unique value that is well appreciated by most customers who use CBD products.
How Is Extraction Process
There are virtually two major ways for CBD extraction. These techniques include:
- Alcohol extraction method
- Carbon dioxide extraction method
Alcohol Extraction Method
This is by far the most common, cheapest and easiest way to extract CBD from whole plants. It is the original method to be developed for the purpose of extracting CBD. Its invention is credited to one, Rick Simpson – the gentleman who came up with this idea.
The initial step is started by soaking the CBD plant in a suitable solvent (alcohol in this case). When the solvent evaporates the resultant mixture is the pure CBD oil.
The process of evaporating the solvent is achieved in the Roto vap – a section which heats the solvent to speed up the evaporation process. The good thing about using Roto vap in the evaporation chamber is that the solvent is not lost. It is able to capture the solvent for later reuse.
The oil is afterward left behind in the chambers and subsequently ready for consumption. Commercial producers have recently modified Simpson’s method and are using ethanol instead of alcohol as the solvent for extracting CBD.
Carbon Dioxide Extraction Method
Carbon dioxide extraction is the alternative method to Simpson’s method. However, it is a more complex method, which requires more tools and is somewhat expensive. This method requires that you force carbon dioxide through the cannabis plant under controlled pressure and temperature to extract CBD.
The process requires a serious of chambers whose chief purpose is to regulate both temperature and pressure into levels that are conducive for the process. In these chambers, the prevailing conditions enable carbon dioxide to react with the cannabinoids from cannabis making them separate.
Conveniently, the chambers in this process are organized in such a way that certain components of the cannabinoids can be extracted separately. This is the major advantage of this process because you WILL not only produce cannabidiol CBD oil but also other cannabinoids in separate chambers.
For a better experience, the product needs to be made more palatable to make it easy for consumers to incorporate it into their daily routine. This is where flavoring comes in. Quite a number of flavors are used to diversify the presence of CBD in a product.
Depending on the need, the extracted cannabidiol oil should also be diluted in proportions which ensure that its strength is appropriately reduced while maintaining its potency. It’s daunting to create your own CBD product, but the good news is you don’t have to do because there are many effective and affordable brands to buy in the market.
CBD Oil Uses
CBD is popular for its health benefits. In this section, we will cover the different things about it from what it is used for to how it is being used for medication.
There are several uses for CBD oils especially when it comes to health benefits. This is used by many as a treatment for anxiety disorder, inflammation, sleep disorders, depression, epilepsy and pain.
CBD is one of the most potent pain relievers. It can manage both acute and chronic pain. It is also effective against other symptoms of inflammation such as swelling, and restoration of function in affected parts of the body.
What does CBD Oil do for you?
CBD oil is not a curative agent per se, but more of an agent to provide symptomatic relief. This means that irrespective of the disease you are managing with CBD oil, your symptoms will certainly come back if you stop your therapy regimen.
Most diseases are accompanied by inflammatory responses which cause pain, swelling, loss of function and occasionally – redness. CBD is a potent anti-inflammatory agent which effectively manages the symptoms of inflammation hence the reason why it is widely used in a number of diseases.
Besides, it is also very selective to damaged cells and spares normal cells which reduce the possibility of suffering from adverse effects secondary to using a CBD oil.
CBD also has potent neuroprotective benefits which make it useful in the management of most of the diseases affecting the central nervous system.
Here are the most common conditions that can be managed by CBD oils:
The field of medicine achieved a great milestone in the month of June 2018 when the Food and Drug Administration approved the drug Epidiolex for use in the management of certain types of seizures.
What makes this more interesting is that Epidiolex is actually an analogue of CBD oil. This essentially means that the FDA has approved CBD for the management of seizures.
But what do the people who have tried this say about its effectiveness in managing seizures?
Actually, most people who suffer from seizures are always wary of stopping their medications to settle for CBD medications. Besides, it may take quite some time for CBD oil to fully augment the function of your endocannabinoid system – depending on how your body responds to it.
On average, most people start noticing results within a month after starting management of seizures using CBD. That’s why those who have tried it say that you should be patient with CBD for epilepsy. This is particularly effective for grand mal seizures.
Cancer is a menace that has been increasingly affecting most people worldwide. There are several genetic mechanisms that are linked to the development and progression of cancer. Several studies have proven the effectiveness of CBD in the management of cancer.
For instance, the progression greatly depends on the formation of new blood vessels within the cancer cells – a process called angiogenesis. This study characteristically found out that CBD is an active inhibitor of angiogenesis. Impaired blood supply reduces the progression of cancer cells.
Besides, cancer cells migrate to other organs in the body by a process called metastasis. Metastasis occurs when cancer cells first invade the underlying tissues and enter the bloodstream or lymphatics. This study found out that CBD (Cannabidiol) actively inhibits cancer cell invasion by upregulating inhibitors of the enzymes used by these cancer cells to invade and metastasize.
It is also worth mentioning that this study found out that CBD has properties that increase its efficacy in the management of a certain type of cancer called neuroblastoma. It does this by preventing the invasion of this tumor to the adjacent tissues.
3. Anxiety and Depression
The incidence and prevalence of anxiety and depression have significantly reduced among individuals who have incorporated the use of CBD oil into their daily regimen. More and more are turning to CBD to address this problem and if you are interested, you can find the best brands to buy here.
CBD is a potent agonist at the 5-HT1A serotonergic receptor which is very important in the regulation of anxiety and depression. It can be safely administered acutely (your doctor will say administer as needed) because it is well tolerated and has no significant adverse side effects.
Acne is a skin condition that occurs when the hair follicles in your skin become clogged with excess fat or dead skin cells. It presents majorly as blackheads, whiteheads or pimples. Conveniently, hair follicles contain CB 2 receptors – the receptors which are the appropriate binding sites for CBD.
At the receptor level, CBD is an active anti-inflammatory agent which treats acne in more ways than one. It also releases certain cytokines such as anandamide which regulates the growth and proliferation of cells. Unregulated cell growth causes clogging of dead cells within the hair follicles which leads to acne.
The benefit that CBD has over prescription medications for the management of acne is that it is very specific and only targets the cells causing the problem. It leaves the normal cells which effectively reduces the chances of experiencing any side effects.
5. Cardiovascular Diseases
The diseases that are found in this category include stroke, coronary heart disease, rheumatic heart disease and hypertension. Studies have shown that CBD can cause relaxation of blood vessels. This reduction in the tension of muscular wall supporting the blood vessels is an effective mechanism against hypertension.
A single dose of cannabidiol can reduce blood pressure in the selected subjects. However, its effects are time-dependent and may not occur instantaneously.
Studies done using animal models have proved that CBD is highly effective when used as an antipsychotic agent. Pharmacologically, it has been proven that CBD oil is just as effective as atypical antipsychotics in the management of schizophrenia.
This study found out that CBD can be used as an adjunct therapy for patients with schizophrenia. Its mechanism is also very impressive because it does not actually depend on dopamine receptor antagonism. As a result, studies posit that CBD may be classified as a distinct class of medication in the management of this disorder.
7. Treatment of Substance Abuse
Most people have raised the question as to whether CBD has addictive and psychotic potential like THC – the largest component among the cannabinoids. The truth however is; CBD can be used to treat the symptoms of THC.
CBD acts on major neurotransmission systems that are actively involved in mediating addiction. This effect is similar when this is used to manage stress, anxiety disorders and neurotoxicity. However, no trials have been successfully done using human subjects to provide a conclusive clinical finding.
Other disease conditions whose symptoms can be managed by CBD Oil include:
- Breast Cancer
- Diabetes Prevention
- Hormonal imbalance
- Alzheimer’s disease
- Inflammatory bowel disease
- Multiple sclerosis
- Parkinson’s disease
- Post-traumatic stress disorder
How Does CBD Make You Feel
CBD is very different from THC as unlike the latter, it does not cause any psychoactive effects. Instead, it makes you feel relaxed, eases your stress and reduces the chances that you will experience anxiety or depression.
Most people have marijuana based reservations which keep them from trying out CBD oil but that should not be the case. CBD should be fully incorporated in your daily activities to help you manage insomnia, fatigue as in jet lag, stress and inflammatory process in your skin or body.
CBD oil and its benefits are the current trends in medicine and diseases management. At least everyone should be well acquainted with the basic information about CBD. It can be very helpful in virtually any type of disease – from the most adverse like cancer to the least of concern like minor inflammations of the skin.
You should appreciate the CBD works variably among people because the biochemistry of the body is significantly different in everyone at the molecular level. As a result, you should be patient with yourself and consult a professional if you are not sure about the right course to take in matters CBD oil.
- Zanelati TV, Biojone C, Moreira FA, Guimaraes FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. Br J Pharmacol. 2010;159(1):122–8.
- Thomas A, Baillie GL, Phillips AM, Razdan RK, Ross RA, Pertwee RG. Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. Br J Pharmacol. 2007;150(5):613–23.
- Bisogno T, Hanus L, De Petrocellis L, et al. Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide. Br J Pharmacol. 2001;134(4):845–52.
- Figueredo VM. The time has come for physicians to take notice: the impact of psychosocial stressors on the heart. Am J Med. 2009;122(8):704–712.
- Stanley CP, Hind WH, O’Sullivan SE. Is the cardiovascular system a therapeutic target for cannabidiol? Br J Clin Pharmacol. 2013;75(2):313–322.
- Capasso R, Borrelli F, Aviello G, Romano B, Scalisi C, Capasso F, Izzo AA. Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice. Br J Pharmacol. 2008; 154:1001–8.
- Iuvone T, Esposito G, De Filippis D, Scuderi C, Steardo L. Cannabidiol: a promising drug for neurodegenerative disorders? CNS Neurosci Ther. 2009; 15:65–75.
- Randall DM, Kendall AD, O’Sullivan SE. The complexities of the cardiovascular actions of cannabinoids. Br J Pharmacol. 2004; 142:20–6.